Drop D tuning is what I usually use for this intro. You can go with Drop C aswell.
I think this is a guitar, could aswell be a synth. Anywho, here's where to play it:
|-----------------------------------------------------------------------------|
|-15-15--15-15-15--15-14-14--14-14-14--14-12-12--12-12-12--12-12-12--12-12-14-|
|-----------------------------------------------------------------------------|
|-----------------------------------------------------------------------------|
|-----------------------------------------------------------------------------|
|-----------------------------------------------------------------------------|
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|-15-15--15-15-15--15-14-14--14-14-14--14-12~~~~-------|
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Guitar 2:
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|------------------------------------------------------|
|------------------------------------------------------|
|-5-5--5-5-5--5-4-4--4-4-4--4-2-2--2-2-2--2-2-2--2-2-4-|
|-5-5--5-5-5--5-4-4--4-4-4--4-2-2--2-2-2--2-2-2--2-2-4-|
|-5-5--5-5-5--5-4-4--4-4-4--4-2-2--2-2-2--2-2-2--2-2-4-|
|------------------------------------------------------|
|------------------------------------------------------|
|------------------------------------------------------|
|-5-5--5-5-5--5-4-4--4-4-4--4-2~~~---------------------|
|-5-5--5-5-5--5-4-4--4-4-4--4-2~~~---------------------|
|-5-5--5-5-5--5-4-4--4-4-4--4-2~~~---------------------|
|-12-11-9--8--6--4--6--8--9--2-------------------------|
|------------------------------------------------------|
|------------------------------------------------------|
|------------------------------------------------------|
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|-12-11-9--8--6--4--6~~~-------------------------------|
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And then comes the verse.